3UAJ

Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (B, A)	envelope protein	polymer	433	47285.5	2	UniProt (Q91AI1) Pfam (PF00869) Pfam (PF02832) UniProt (by SIFTS) (P09866)	Dengue virus 4
2	B, E (H, C)	Heavy chain, monoclonal antibody 5H2	polymer	236	25070.0	2		Pan troglodytes (chimpanzee)
3	C, F (L, D)	Light chain, monoclonal antibody 5H2	polymer	215	23493.0	2		Pan troglodytes (chimpanzee)
4	G, H (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

B, A: 1 - 395 (UniProt: Q91AI1)

PDB	External Database	Details
Pro 396	-	expression tag
Phe 397	-	expression tag
Glu 398	-	expression tag
Asp 399	-	expression tag
Asp 400	-	expression tag
Asp 401	-	expression tag
Asp 402	-	expression tag
Lys 403	-	expression tag
Ala 404	-	expression tag
Gly 405	-	expression tag
Trp 406	-	expression tag
Ser 407	-	expression tag
His 408	-	expression tag
Pro 409	-	expression tag
Gln 410	-	expression tag
Phe 411	-	expression tag
Glu 412	-	expression tag
Lys 413	-	expression tag
Gly 414	-	expression tag
Gly 415	-	expression tag
Gly 416	-	expression tag
Ser 417	-	expression tag
Gly 418	-	expression tag
Gly 419	-	expression tag
Gly 420	-	expression tag
Ser 421	-	expression tag
Gly 422	-	expression tag
Gly 423	-	expression tag
Gly 424	-	expression tag
Ser 425	-	expression tag
Trp 426	-	expression tag
Ser 427	-	expression tag
His 428	-	expression tag
Pro 429	-	expression tag
Gln 430	-	expression tag
Phe 431	-	expression tag
Glu 432	-	expression tag
Lys 433	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	191697.0
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	192139.5

*Water molecules are not included.