3TG5
Structure of SMYD2 in complex with p53 and SAH
Summary for 3TG5
Entry DOI | 10.2210/pdb3tg5/pdb |
Related | 3TG4 |
Descriptor | N-lysine methyltransferase SMYD2, Cellular tumor antigen p53, GLYCEROL, ... (6 entities in total) |
Functional Keywords | set domain, methyltransferase, co factor binding, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytosol (By similarity): Q9NRG4 Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
Total number of polymer chains | 2 |
Total formula weight | 51674.25 |
Authors | |
Primary citation | Wang, L.,Li, L.,Zhang, H.,Luo, X.,Dai, J.,Zhou, S.,Gu, J.,Zhu, J.,Atadja, P.,Lu, C.,Li, E.,Zhao, K. Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation J.Biol.Chem., 2011 Cited by PubMed: 21880715DOI: 10.1074/jbc.M111.262410 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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