3T96

Iodowillardiine bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2

Summary for 3T96

• Entry DOI: 10.2210/pdb3t96/pdb
• Related: 3T93 3T9H 3T9U 3T9V 3T9X
• Descriptor: Glutamate receptor 2, 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, ... (4 entities in total)
• Functional Keywords: s1s2, neurotransmitter receptor, transport protein
• Biological source: Rattus norvegicus (rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 3
• Total formula weight: 87952.59

Authors

Ahmed, A.H.,Wang, S.,Chuang, H.H.,Oswald, R.E. (deposition date: 2011-08-02, release date: 2011-08-17, Last modification date: 2023-09-13)

• Primary citation: Ahmed, A.H.,Wang, S.,Chuang, H.H.,Oswald, R.E.; Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.; J.Biol.Chem., 286:35257-35266, 2011; PubMed: 21846932; DOI: 10.1074/jbc.M111.269001

Experimental method

X-RAY DIFFRACTION (1.872 Å)