3T96
Iodowillardiine bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, D, F | Glutamate receptor 2 | polymer | 258 | 28883.5 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (rat) | GluA2, GluR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2 |
2 | B, D, F | 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID | non-polymer | 325.1 | 3 | Chemie (IWD) | |||
3 | B, D, F | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
4 | water | water | 18.0 | 1080 | Chemie (HOH) |
Sequence modifications
B, D, F: 4 - 117 (UniProt: P19491)
B, D, F: 120 - 261 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Cys 63 | Ala 473 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | linker |
Thr 119 | - | linker |
Cys 140 | Ser 673 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 86650.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1302.2 | |
All* | Total formula weight | 87952.6 |