Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
B | 0016020 | cellular_component | membrane |
D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
D | 0016020 | cellular_component | membrane |
F | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
F | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE IWD B 601 |
Chain | Residue |
B | TYR61 |
B | THR174 |
B | LEU192 |
B | GLU193 |
B | TYR220 |
B | HOH275 |
B | HOH279 |
B | PRO89 |
B | LEU90 |
B | THR91 |
B | ARG96 |
B | LEU138 |
B | GLY141 |
B | SER142 |
B | THR143 |
site_id | AC2 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE IWD D 601 |
Chain | Residue |
D | TYR61 |
D | PRO89 |
D | LEU90 |
D | THR91 |
D | ARG96 |
D | LEU138 |
D | GLY141 |
D | SER142 |
D | THR143 |
D | THR174 |
D | LEU192 |
D | GLU193 |
D | TYR220 |
D | HOH265 |
D | HOH280 |
site_id | AC3 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE IWD F 601 |
Chain | Residue |
F | HOH3 |
F | TYR61 |
F | PRO89 |
F | LEU90 |
F | THR91 |
F | ARG96 |
F | LEU138 |
F | GLY141 |
F | SER142 |
F | THR143 |
F | THR174 |
F | LEU192 |
F | GLU193 |
F | TYR220 |
F | HOH269 |
F | HOH271 |
F | HOH294 |
site_id | AC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE ZN B 1 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ZN B 2 |
Chain | Residue |
B | GLU42 |
B | HIS46 |
F | GLU166 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN D 3 |
Chain | Residue |
D | HIS23 |
D | GLU24 |
F | LYS20 |
F | HIS23 |
F | GLU30 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ZN D 262 |
Chain | Residue |
D | GLU42 |
D | HIS46 |
D | HOH1004 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN F 262 |
Chain | Residue |
B | GLU166 |
F | GLU42 |
F | HIS46 |
F | GLN244 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | PRO89 | |
D | SER142 | |
D | THR143 | |
D | GLU193 | |
F | PRO89 | |
F | THR91 | |
F | ARG96 | |
F | SER142 | |
F | THR143 | |
F | GLU193 | |
B | THR91 | |
B | ARG96 | |
B | SER142 | |
B | THR143 | |
B | GLU193 | |
D | PRO89 | |
D | THR91 | |
D | ARG96 | |
site_id | SWS_FT_FI2 |
Number of Residues | 9 |
Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
B | ARG64 | |
B | ARG148 | |
B | LYS240 | |
D | ARG64 | |
D | ARG148 | |
D | LYS240 | |
F | ARG64 | |
F | ARG148 | |
F | LYS240 | |
site_id | SWS_FT_FI3 |
Number of Residues | 3 |
Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
Chain | Residue | Details |
B | ILE121 | |
D | ILE121 | |
F | ILE121 | |
Chain | Residue | Details |
B | SER150 | |
D | SER150 | |
F | SER150 | |
Chain | Residue | Details |
B | SER184 | |
D | SER184 | |
F | SER184 | |