3T11

Dimeric inhibitor of HIV-1 protease.

Summary for 3T11

• Entry DOI: 10.2210/pdb3t11/pdb
• Descriptor: HIV-1 Protease, (3S,11S)-11-(3-chloro-4-hydroxy-5-methoxyphenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: hiv-1 protease, beta barel, retroviral aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus type 1 (HIV-1)
• Cellular location: Gag-Pol polyprotein: Host cell membrane ; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03367
• Total number of polymer chains: 2
• Total formula weight: 22693.08

Authors

Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J. (deposition date: 2011-07-21, release date: 2012-08-22, Last modification date: 2023-09-13)

• Primary citation: Brynda, J.,Rezacova, P.,Saskova, G.K.,Kozisek, M.,Konvalinka, J.; Dimeric inhibitor of HIV-1 protease.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.22 Å)