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3SV2

Human Thrombin In Complex With UBTHR105

Summary for 3SV2
Entry DOI10.2210/pdb3sv2/pdb
Related3P17 3QTO 3QTV 3QWC 3QX5 3SHA
Related PRD IDPRD_000795
DescriptorThrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
Functional Keywordsserine protease, kringle, hydrolase, blood coagulation, blood clotting, convertion of fibrinogen to fibrin, cleavage on pairs of basic residues, hirudin, glycosylation, blood, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight36530.31
Authors
Biela, A.,Heine, A.,Klebe, G. (deposition date: 2011-07-12, release date: 2012-06-20, Last modification date: 2023-12-06)
Primary citationBiela, A.,Khayat, M.,Tan, H.,Kong, J.,Heine, A.,Hangauer, D.,Klebe, G.
Impact of ligand and protein desolvation on ligand binding to the S1 pocket of thrombin
J.Mol.Biol., 418:350-366, 2012
Cited by
PubMed: 22366545
DOI: 10.1016/j.jmb.2012.01.054
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

217705

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