3SIS

Crystal structure of Porcine CRW-8 Rotavirus VP8* in complex with aceramido-GM3_Gc

Summary for 3SIS

• Entry DOI: 10.2210/pdb3sis/pdb
• Related: 2I2S 3SIT
• Descriptor: Outer capsid protein VP4, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, methyl 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid, ... (6 entities in total)
• Functional Keywords: beta sandwich, lectin, gm3, sugar binding protein, viral protein
• Biological source: Porcine rotavirus (RV-A)
• Cellular location: Outer capsid protein VP4: Virion. Outer capsid protein VP8*: Virion. Outer capsid protein VP5*: Virion: P0C6Y8
• Total number of polymer chains: 2
• Total formula weight: 38072.03

Authors

Blanchard, H.,Yu, X. (deposition date: 2011-06-20, release date: 2011-09-28, Last modification date: 2023-09-13)

• Primary citation: Yu, X.,Coulson, B.S.,Fleming, F.E.,Dyason, J.C.,von Itzstein, M.,Blanchard, H.; Novel structural insights into rotavirus recognition of ganglioside glycan receptors.; J.Mol.Biol., 413:929-939, 2011; PubMed: 21945555; DOI: 10.1016/j.jmb.2011.09.005

Experimental method

X-RAY DIFFRACTION (2.2 Å)