3SIS
Crystal structure of Porcine CRW-8 Rotavirus VP8* in complex with aceramido-GM3_Gc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Outer capsid protein VP4 | polymer | 163 | 18459.5 | 2 | UniProt (P0C6Y8) Pfam (PF00426) In PDB | Porcine rotavirus (RV-A) | VP8* carbohydrate recognition protein |
| 2 | C | N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | branched | 649.6 | 1 | In PDB GlyTouCan (G50281RU) | |||
| 3 | A | methyl 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid | non-polymer | 339.3 | 1 | Chemie (MN0) | |||
| 4 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A, B: 64 - 224 (UniProt: P0C6Y8)
| PDB | External Database | Details |
|---|---|---|
| Gly 62 | - | expression tag |
| Ser 63 | - | expression tag |
| Gln 70 | Arg 70 | engineered mutation |
| Ile 82 | Val 82 | engineered mutation |
| Asn 151 | Ser 151 | engineered mutation |
| Ser 201 | Leu 201 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36919.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 649.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 503.5 | |
| All* | Total formula weight | 38072.0 |
