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3SH7

Crystal structure of fluorophore-labeled beta-lactamase PenP

Replaces:  3KGM
Summary for 3SH7
Entry DOI10.2210/pdb3sh7/pdb
Related3SH8 3SH9
DescriptorBeta-lactamase, 1-[6-(dimethylamino)naphthalen-2-yl]ethanone (3 entities in total)
Functional Keywordsbeta-lactamase, fluorophore, beta-lactam, hydrolase
Biological sourceBacillus licheniformis
Cellular locationCell membrane; Lipid-anchor (Probable): P00808
Total number of polymer chains2
Total formula weight59721.87
Authors
Wong, W.-T.,Zhao, Y.-X.,Leung, Y.-C. (deposition date: 2011-06-16, release date: 2011-07-27, Last modification date: 2024-03-20)
Primary citationWong, W.-T.,Chan, K.-C.,So, P.-K.,Yap, H.-K.,Chung, W.-H.,Leung, Y.-C.,Wong, K.-Y.,Zhao, Y.-X.
Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics
J.Biol.Chem., 286:31771-31780, 2011
Cited by
PubMed: 21705325
DOI: 10.1074/jbc.M110.198895
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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