3S5D
Crystal structure of human frataxin variant W155A
Summary for 3S5D
Entry DOI | 10.2210/pdb3s5d/pdb |
Related | 3S4M 3S5E 3S5F |
Descriptor | Frataxin, mitochondrial, SULFATE ION (3 entities in total) |
Functional Keywords | allosteric activator, mitochondrion, alpha beta 2-layer sandwich, unknown function |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q16595 |
Total number of polymer chains | 1 |
Total formula weight | 14176.58 |
Authors | Tsai, C.-L.,Bridwell-Rabb, J.,Barondeau, D.P. (deposition date: 2011-05-23, release date: 2011-06-29, Last modification date: 2023-09-13) |
Primary citation | Tsai, C.L.,Bridwell-Rabb, J.,Barondeau, D.P. Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex. Biochemistry, 50:6478-6487, 2011 Cited by PubMed: 21671584DOI: 10.1021/bi200666h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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