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3S4M

Crystal structure of wild-type human frataxin

Summary for 3S4M
Entry DOI10.2210/pdb3s4m/pdb
Related3S5D 3S5E 3S5F
DescriptorFrataxin, mitochondrial (2 entities in total)
Functional Keywordsallosteric activator, mitochondrion, alpha beta 2-layer sandwich, unknown function
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q16595
Total number of polymer chains1
Total formula weight14195.65
Authors
Tsai, C.-L.,Bridwell-Rabb, J.,Barondeau, D.P. (deposition date: 2011-05-19, release date: 2011-06-29, Last modification date: 2023-09-13)
Primary citationTsai, C.L.,Bridwell-Rabb, J.,Barondeau, D.P.
Friedreich's Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex.
Biochemistry, 50:6478-6487, 2011
Cited by
PubMed: 21671584
DOI: 10.1021/bi200666h
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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