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3RHY

Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine

Summary for 3RHY
Entry DOI10.2210/pdb3rhy/pdb
Related1H70 3BPB
DescriptorN(G),N(G)-dimethylarginine dimethylaminohydrolase, (4-chloropyridin-2-yl)methanol (3 entities in total)
Functional Keywordsenzyme adduct, hydrolase
Biological sourcePseudomonas aeruginosa
Total number of polymer chains2
Total formula weight57300.18
Authors
Monzingo, A.F.,Johnson, C.M.,Ke, Z.,Yoon, D.-W.,Linsky, T.W.,Guo, H.,Fast, W.,Robertus, J.D. (deposition date: 2011-04-12, release date: 2011-06-15, Last modification date: 2023-09-13)
Primary citationJohnson, C.M.,Monzingo, A.F.,Ke, Z.,Yoon, D.W.,Linsky, T.W.,Guo, H.,Robertus, J.D.,Fast, W.
On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines.
J.Am.Chem.Soc., 133:10951-10959, 2011
Cited by
PubMed: 21630706
DOI: 10.1021/ja2033684
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.18 Å)
Structure validation

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