3RBU
N-terminally AviTEV-tagged Human Glutamate Carboxypeptidase II in complex with 2-PMPA
Summary for 3RBU
Entry DOI | 10.2210/pdb3rbu/pdb |
Descriptor | Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | peptidase, biotinylation, extracellular, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type II membrane protein. Isoform PSMA': Cytoplasm: Q04609 |
Total number of polymer chains | 1 |
Total formula weight | 86480.67 |
Authors | Tykvart, J.,Sacha, P.,Barinka, C.,Starkova, J.,Knedlik, T.,Lubkowski, J.,Konvalinka, J. (deposition date: 2011-03-30, release date: 2012-01-04, Last modification date: 2023-09-13) |
Primary citation | Tykvart, J.,Sacha, P.,Barinka, C.,Knedlik, T.,Starkova, J.,Lubkowski, J.,Konvalinka, J. Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II. Protein Expr.Purif., 82:106-115, 2012 Cited by PubMed: 22178733DOI: 10.1016/j.pep.2011.11.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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