3QXM
Crystal Structure of Human GluK2 Ligand-Binding Core in Complex with Novel Marine-Derived Toxins, Neodysiherbaine A
Summary for 3QXM
Entry DOI | 10.2210/pdb3qxm/pdb |
Related | 2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FVG 3FVK 3FVN 3FVO |
Descriptor | Glutamate receptor ionotropic, kainate 2, (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid (3 entities in total) |
Functional Keywords | two domains, ligand-binding, membrane protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: Q13002 |
Total number of polymer chains | 2 |
Total formula weight | 59155.56 |
Authors | Unno, M.,Sasaki, M.,Ikeda-Saito, M. (deposition date: 2011-03-02, release date: 2011-10-26, Last modification date: 2023-11-01) |
Primary citation | Unno, M.,Shinohara, M.,Takayama, K.,Tanaka, H.,Teruya, K.,Doh-Ura, K.,Sakai, R.,Sasaki, M.,Ikeda-Saito, M. Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors. J.Mol.Biol., 413:667-683, 2011 Cited by PubMed: 21893069DOI: 10.1016/j.jmb.2011.08.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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