3FVN
Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with 9-deoxy-neodysiherbaine A in space group P1
Summary for 3FVN
Entry DOI | 10.2210/pdb3fvn/pdb |
Related | 2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FV2 3FVG 3FVK 3FVO |
Descriptor | Glutamate receptor, ionotropic kainate 1, GLYCEROL, (2R,3aR,7R,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-7-hydroxy-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid, ... (5 entities in total) |
Functional Keywords | glutamate receptor, ligand-binding domain, 9-deoxy-neodysiherbaine, membrane protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P39086 |
Total number of polymer chains | 2 |
Total formula weight | 59762.33 |
Authors | Unno, M.,Sasaki, M.,Ikeda-Saito, M. (deposition date: 2009-01-16, release date: 2010-01-19, Last modification date: 2023-11-01) |
Primary citation | Unno, M.,Shinohara, M.,Takayama, K.,Tanaka, H.,Teruya, K.,Doh-Ura, K.,Sakai, R.,Sasaki, M.,Ikeda-Saito, M. Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors. J.Mol.Biol., 413:667-683, 2011 Cited by PubMed: 21893069DOI: 10.1016/j.jmb.2011.08.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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