3QVG

XRCC1 bound to DNA ligase

Summary for 3QVG

• Entry DOI: 10.2210/pdb3qvg/pdb
• Related: 3PC6 3PC7 3PC8
• Descriptor: DNA ligase 3, DNA repair protein XRCC1 (3 entities in total)
• Functional Keywords: brct domain, dna repair, xrcc1, dna ligase iii-alpha, dna binding protein-ligase complex, dna binding protein/ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Mitochondrion . Isoform 2: Mitochondrion . Isoform 3: Nucleus . Isoform 4: Nucleus : P49916; Nucleus : Q60596
• Total number of polymer chains: 4
• Total formula weight: 45485.47

Authors

Cuneo, M.J.,Krahn, J.M.,London, R.E. (deposition date: 2011-02-25, release date: 2011-06-15, Last modification date: 2023-09-13)

• Primary citation: Cuneo, M.J.,Gabel, S.A.,Krahn, J.M.,Ricker, M.A.,London, R.E.; The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.; Nucleic Acids Res., 39:7816-7827, 2011; PubMed: 21652643; DOI: 10.1093/nar/gkr419

Experimental method

X-RAY DIFFRACTION (2.26 Å)