3QVG

XRCC1 bound to DNA ligase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	DNA ligase 3	polymer	89	10113.5	2	UniProt (P49916) Pfam (PF16759)	Homo sapiens (human)	DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3
2	B, D (B, D)	DNA repair protein XRCC1	polymer	106	12629.3	2	UniProt (Q60596) Pfam (PF16589)	Mus musculus (mouse)	X-ray repair cross-complementing protein 1
3	E, F, G, H (A, B, C, D)	water	water		18.0	297	Chemie (HOH)

Sequence modifications

A, C: 837 - 921 (UniProt: P49916)

PDB	External Database	Details
Ser 834	-	expression tag
Asn 835	-	expression tag
Ser 836	-	expression tag
Ser 922	-	expression tag

B, D: 531 - 631 (UniProt: Q60596)

PDB	External Database	Details
Met 526	-	expression tag
Gln 527	-	expression tag
Glu 528	-	expression tag
Pro 529	-	expression tag
Pro 530	-	expression tag
Val 534	Ile 534	engineered mutation
Arg 574	Tyr 574	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	45485.5
All*	Total formula weight	45485.5

*Water molecules are not included.