3QT2
Structure of a cytokine ligand-receptor complex
Summary for 3QT2
Entry DOI | 10.2210/pdb3qt2/pdb |
Descriptor | Interleukin-5 receptor subunit alpha, Interleukin-5, beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cytokine type i receptor fold, fibronectin type iii modules, four-helical bundle, cytokine, ligand-receptor complex, membrane, protein binding-immune system complex, protein binding/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 126908.43 |
Authors | Mueller, T.D.,Patino, E.,Kotzsch, A.,Saremba, S.,Nickel, J.,Schmitz, W.,Sebald, W. (deposition date: 2011-02-22, release date: 2012-02-01, Last modification date: 2020-07-29) |
Primary citation | Patino, E.,Kotzsch, A.,Saremba, S.,Nickel, J.,Schmitz, W.,Sebald, W.,Mueller, T.D. Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha. Structure, 19:1864-1875, 2011 Cited by PubMed: 22153509DOI: 10.1016/j.str.2011.08.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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