3QLP
X-ray structure of the complex between human alpha thrombin and a modified thrombin binding aptamer (mTBA)
Summary for 3QLP
Entry DOI | 10.2210/pdb3qlp/pdb |
Related PRD ID | PRD_000020 |
Descriptor | Thrombin heavy chain, Thrombin light chain, modified thrombin binding DNA aptamer, ... (8 entities in total) |
Functional Keywords | protein-dna complex, serine protease, blood coagulation, aptamer, serine protease fold, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 39357.09 |
Authors | Russo Krauss, I.,Merlino, A.,Mazzarella, L.,Sica, F. (deposition date: 2011-02-03, release date: 2011-10-19, Last modification date: 2020-07-29) |
Primary citation | Russo Krauss, I.,Merlino, A.,Giancola, C.,Randazzo, A.,Mazzarella, L.,Sica, F. Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res., 39:7858-7867, 2011 Cited by PubMed: 21715374DOI: 10.1093/nar/gkr522 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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