3PHX

OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15

Summary for 3PHX

• Entry DOI: 10.2210/pdb3phx/pdb
• Related: 3PHU 3PHW
• Descriptor: RNA-directed RNA polymerase L, Ubiquitin-like protein ISG15, ZINC ION, ... (6 entities in total)
• Functional Keywords: otu domain, de-ubiquitinase, de-isgylase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Crimean-Congo hemorrhagic fever virus (CCHFV); More
• Cellular location: Cytoplasm: P05161
• Total number of polymer chains: 2
• Total formula weight: 30946.94

Authors

Akutsu, M.,Ye, Y.,Virdee, S.,Komander, D. (deposition date: 2010-11-04, release date: 2011-02-02, Last modification date: 2014-08-06)

• Primary citation: Akutsu, M.,Ye, Y.,Virdee, S.,Chin, J.W.,Komander, D.; Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.; Proc.Natl.Acad.Sci.USA, 108:2228-2233, 2011; PubMed: 21266548; DOI: 10.1073/pnas.1015287108

Experimental method

X-RAY DIFFRACTION (1.6 Å)