3PGF

Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)

Summary for 3PGF

Entry DOI	10.2210/pdb3pgf/pdb
Related PRD ID	PRD_900001
Descriptor	Maltose-binding periplasmic protein, SAB Heavy Chain, SAB Light Chain, ... (7 entities in total)
Functional Keywords	maltodextrin binding protein, fab, antibody fragment, engineered binding protein, maltodextrin binding protein-de novo protein complex, maltodextrin binding protein/de novo protein
Biological source	Escherichia coli More
Cellular location	Periplasm: P0AEX9 Secreted : P0DOX5
Total number of polymer chains	3
Total formula weight	92840.60
Authors	Kossiakoff, A.A.,Duguid, E.M.,Sandstrom, A. (deposition date: 2010-11-01, release date: 2011-03-09, Last modification date: 2023-09-06)
Primary citation	Rizk, S.S.,Paduch, M.,Heithaus, J.H.,Duguid, E.M.,Sandstrom, A.,Kossiakoff, A.A. Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat.Struct.Mol.Biol., 18:437-442, 2011 Cited by PubMed: 21378967 DOI: 10.1038/nsmb.2002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation