3OSL

Structure of bovine thrombin-activatable fibrinolysis inhibitor in complex with tick carboxypeptidase inhibitor

Summary for 3OSL

Entry DOI	10.2210/pdb3osl/pdb
Related	3D4U 3DGV
Descriptor	Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION (3 entities in total)
Functional Keywords	alpha/beta-hydrolase-related fold, blood, fibrinolysis, coagulation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Rhipicephalus bursa (Tick) More
Cellular location	Secreted : Q2KIG3 Q5EPH2
Total number of polymer chains	4
Total formula weight	108814.33
Authors	Valnickova, Z.,Sanglas, L.,Arolas, J.L.,Petersen, S.V.,Schar, C.,Otzen, D.,Aviles, F.X.,Gomis-Ruth, F.X.,Enghild, J.J. (deposition date: 2010-09-09, release date: 2010-09-29, Last modification date: 2017-11-08)
Primary citation	Valnickova, Z.,Sanglas, L.,Arolas, J.L.,Petersen, S.V.,Schar, C.,Otzen, D.,Aviles, F.X.,Gomis-Ruth, F.X.,Enghild, J.J. Flexibility of the Thrombin-activatable Fibrinolysis Inhibitor Pro-domain Enables Productive Binding of Protein Substrates. J.Biol.Chem., 285:38243-38250, 2010 Cited by PubMed: 20880845 DOI: 10.1074/jbc.M110.150342 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (6 Å)

Structure validation