3OBT
Crystal structure of Botulinum neurotoxin serotype D ligand binding domain in complex with N-Acetylneuraminic acid
Summary for 3OBT
Entry DOI | 10.2210/pdb3obt/pdb |
Related | 3OBR |
Descriptor | Botulinum neurotoxin type D, N-acetyl-beta-neuraminic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | neurotoxin, gangalioside, hydrolase |
Biological source | Clostridium botulinum |
Cellular location | Botulinum neurotoxin D light chain: Secreted. Botulinum neurotoxin D heavy chain: Secreted: P19321 |
Total number of polymer chains | 1 |
Total formula weight | 51642.96 |
Authors | |
Primary citation | Strotmeier, J.,Lee, K.,Volker, A.K.,Mahrhold, S.,Zong, Y.,Zeiser, J.,Zhou, J.,Pich, A.,Bigalke, H.,Binz, T.,Rummel, A.,Jin, R. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner. Biochem.J., 431:207-216, 2010 Cited by PubMed: 20704566DOI: 10.1042/BJ20101042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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