3OAP
Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9-cis retinoic acid and the coactivator peptide GRIP-1
Summary for 3OAP
Entry DOI | 10.2210/pdb3oap/pdb |
Related | 1FBY |
Descriptor | Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, (9cis)-retinoic acid, ... (4 entities in total) |
Functional Keywords | antiparallel sandwich, ligand binding, coactivator binding, dimerization, activation function, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P19793 Q15596 |
Total number of polymer chains | 2 |
Total formula weight | 27603.17 |
Authors | Xia, G.,Smith, C.D.,Muccio, D.D. (deposition date: 2010-08-05, release date: 2010-11-17, Last modification date: 2024-02-21) |
Primary citation | Xia, G.,Boerma, L.J.,Cox, B.D.,Qiu, C.,Kang, S.,Smith, C.D.,Renfrow, M.B.,Muccio, D.D. Structure, Energetics and Dynamics of Binding Coactivator Peptide to Human Retinoid X Receptor Alpha Ligand Binding Domain Complex with 9-cis-Retinoic Acid. Biochemistry, 50:93-105, 2011 Cited by PubMed: 21049972DOI: 10.1021/bi101288y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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