1FBY

CRYSTAL STRUCTURE OF THE HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO 9-CIS RETINOIC ACID

Summary for 1FBY

Entry DOI	10.2210/pdb1fby/pdb
Descriptor	RETINOIC ACID RECEPTOR RXR-ALPHA, (9cis)-retinoic acid (3 entities in total)
Functional Keywords	nuclear receptor, protein-ligand complex, retinoid receptor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P19793
Total number of polymer chains	2
Total formula weight	54110.75
Authors	Egea, P.F.,Mitschler, A.,Rochel, N.,Ruff, M.,Chambon, P.,Moras, D. (deposition date: 2000-07-17, release date: 2000-07-28, Last modification date: 2024-02-07)
Primary citation	Egea, P.F.,Mitschler, A.,Rochel, N.,Ruff, M.,Chambon, P.,Moras, D. Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid. EMBO J., 19:2592-2601, 2000 Cited by PubMed: 10835357 DOI: 10.1093/emboj/19.11.2592 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation