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3O6H

Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator

Summary for 3O6H
Entry DOI10.2210/pdb3o6h/pdb
Related3O28 3O29 3O2A 3O6G 3O6I 3PMV 3PMW 3PMX
DescriptorGlutamate receptor 2, GLUTAMIC ACID, SULFATE ION, ... (7 entities in total)
Functional Keywordstransport protein, membrane protein, fusion protein, chimera protein
Biological sourceRattus norvegicus (rat)
More
Cellular locationCell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains1
Total formula weight30244.72
Authors
Primary citationJamieson, C.,Campbell, R.A.,Cumming, I.A.,Gillen, K.J.,Gillespie, J.,Kazemier, B.,Kiczun, M.,Lamont, Y.,Lyons, A.J.,Maclean, J.K.,Martin, F.,Moir, E.M.,Morrow, J.A.,Pantling, J.,Rankovic, Z.,Smith, L.
A novel series of positive modulators of the AMPA receptor: structure-based lead optimization.
Bioorg.Med.Chem.Lett., 20:6072-6075, 2010
Cited by
PubMed: 20817521
DOI: 10.1016/j.bmcl.2010.08.063
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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