3NY6
Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30
Summary for 3NY6
Entry DOI | 10.2210/pdb3ny6/pdb |
Related | 2Q6M 3ESS 3KI0 3KI1 3KI2 3KI3 3KI4 3KI5 3KI6 3KI7 |
Descriptor | Cholix toxin, GLYCEROL, 2-[(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide, ... (5 entities in total) |
Functional Keywords | alpha-beta complex, adp-ribosyl transferase, nad+ binding, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Vibrio cholerae |
Total number of polymer chains | 1 |
Total formula weight | 23927.40 |
Authors | Merrill, A.R.,Jorgensen, R. (deposition date: 2010-07-14, release date: 2010-12-29, Last modification date: 2023-09-06) |
Primary citation | Turgeon, Z.,Jorgensen, R.,Visschedyk, D.,Edwards, P.R.,Legree, S.,McGregor, C.,Fieldhouse, R.J.,Mangroo, D.,Schapira, M.,Merrill, A.R. Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins. Antimicrob.Agents Chemother., 55:983-991, 2011 Cited by PubMed: 21135177DOI: 10.1128/AAC.01164-10 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
Download full validation report