3NSP

Crystal structure of tetrameric RXRalpha-LBD

Summary for 3NSP

• Entry DOI: 10.2210/pdb3nsp/pdb
• Related: 3NSQ
• Descriptor: Retinoid X receptor, alpha (2 entities in total)
• Functional Keywords: nuclear receptor retinoic x recepor alpha ligand binding domain, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 53712.08

Authors

Zhang, H.,Hu, T.,Li, L.,Zhou, R.,Chen, L.,Hu, L.,Jiang, H.,Shen, X. (deposition date: 2010-07-02, release date: 2010-11-17, Last modification date: 2023-11-01)

• Primary citation: Zhang, H.,Zhou, R.,Li, L.,Chen, J.,Chen, L.,Li, C.,Ding, H.,Yu, L.,Hu, L.,Jiang, H.,Shen, X.; Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.; J.Biol.Chem., 286:1868-1875, 2011; PubMed: 21084305; DOI: 10.1074/jbc.M110.166215

Experimental method

X-RAY DIFFRACTION (2.9 Å)