3NGB
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 gp120
Summary for 3NGB
Entry DOI | 10.2210/pdb3ngb/pdb |
Descriptor | Envelope glycoprotein gp160, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... (9 entities in total) |
Functional Keywords | hiv, gp120, antibody, vrc01, neutralization, vaccine, envelope glycoprotein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 363536.47 |
Authors | Zhou, T.,Kwong, P.D. (deposition date: 2010-06-11, release date: 2010-07-07, Last modification date: 2023-09-06) |
Primary citation | Zhou, T.,Georgiev, I.,Wu, X.,Yang, Z.Y.,Dai, K.,Finzi, A.,Do Kwon, Y.,Scheid, J.F.,Shi, W.,Xu, L.,Yang, Y.,Zhu, J.,Nussenzweig, M.C.,Sodroski, J.,Shapiro, L.,Nabel, G.J.,Mascola, J.R.,Kwong, P.D. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science, 329:811-817, 2010 Cited by PubMed: 20616231DOI: 10.1126/science.1192819 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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