3MNN
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
Summary for 3MNN
Entry DOI | 10.2210/pdb3mnn/pdb |
Related | 2NZD |
Descriptor | Histone H3.2, 1-methyl-4-(1-methylethyl)benzene, 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, ... (12 entities in total) |
Functional Keywords | nucleosome, ncp, ruthenium, rapta-c, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 197692.83 |
Authors | Ong, M.S.,Davey, C.A. (deposition date: 2010-04-22, release date: 2011-04-06, Last modification date: 2023-11-01) |
Primary citation | Wu, B.,Ong, M.S.,Groessl, M.,Adhireksan, Z.,Hartinger, C.G.,Dyson, P.J.,Davey, C.A. A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core Chemistry, 17:3562-3566, 2011 Cited by PubMed: 21344528DOI: 10.1002/chem.201100298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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