3MDJ

ER Aminopeptidase, ERAP1, Bound to the Zinc Aminopeptidase Inhibitor, Bestatin

Summary for 3MDJ

Entry DOI	10.2210/pdb3mdj/pdb
Descriptor	Endoplasmic reticulum aminopeptidase 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	aminopeptidase, zn binding protein, er, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	319747.22
Authors	Nguyen, T.T.,Stern, L.J. (deposition date: 2010-03-30, release date: 2011-03-30, Last modification date: 2023-09-06)
Primary citation	Nguyen, T.T.,Chang, S.C.,Evnouchidou, I.,York, I.A.,Zikos, C.,Rock, K.L.,Goldberg, A.L.,Stratikos, E.,Stern, L.J. Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat.Struct.Mol.Biol., 18:604-613, 2011 Cited by PubMed: 21478864 DOI: 10.1038/nsmb.2021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation