3MDJ
ER Aminopeptidase, ERAP1, Bound to the Zinc Aminopeptidase Inhibitor, Bestatin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Endoplasmic reticulum aminopeptidase 1 | polymer | 921 | 105238.7 | 3 | UniProt (Q9NZ08) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Homo sapiens (human) | Adipocyte-derived leucine aminopeptidase, A-LAP, ARTS-1, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator |
2 | D, F | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
3 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B, C | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
5 | A, B, C | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID | non-polymer | 308.4 | 3 | Chemie (BES) | |||
6 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B, C: 37 - 939 (UniProt: Q9NZ08)
PDB | External Database | Details |
---|---|---|
Asp 346 | Gly 346 | SEE REMARK 999 |
Arg 514 | Gly 514 | SEE REMARK 999 |
Arg 528 | Lys 528 | SEE REMARK 999 |
Glu 730 | Gln 730 | SEE REMARK 999 |
His 940 | - | expression tag |
Asp 941 | - | expression tag |
Pro 942 | - | expression tag |
Glu 943 | - | expression tag |
Ala 944 | - | expression tag |
Asp 945 | - | expression tag |
Ala 946 | - | expression tag |
Thr 947 | - | expression tag |
Gly 948 | - | expression tag |
Leu 949 | - | expression tag |
Glu 950 | - | expression tag |
Arg 951 | - | expression tag |
Met 952 | - | expression tag |
Leu 953 | - | expression tag |
Glu 954 | - | expression tag |
Ser 955 | - | expression tag |
Arg 956 | - | expression tag |
Gly 957 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 315716.2 | |
Branched | Number of molecules | 3 |
Total formula weight | 2246.0 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1785.0 | |
All* | Total formula weight | 319747.2 |