3KYM
Crystal structure of Li33 IgG2 di-Fab
Summary for 3KYM
Entry DOI | 10.2210/pdb3kym/pdb |
Related | 3KYK |
Descriptor | Light Chain Li33 IgG2, Heavy Chain Li33 IgG2 (2 entities in total) |
Functional Keywords | igg2 monoclonal anti-lingo, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 16 |
Total formula weight | 383291.56 |
Authors | Silvian, L.F.,Pepinsky, R.B.,Walus, L. (deposition date: 2009-12-06, release date: 2010-03-16, Last modification date: 2023-09-06) |
Primary citation | Pepinsky, R.B.,Silvian, L.,Berkowitz, S.A.,Farrington, G.,Lugovskoy, A.,Walus, L.,Eldredge, J.,Capili, A.,Mi, S.,Graff, C.,Garber, E. Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis. Protein Sci., 19:954-966, 2010 Cited by PubMed: 20198683DOI: 10.1002/pro.372 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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