3IXA

Human Class I MHC HLA-A2(A150P) in complex with the Tax peptide

Summary for 3IXA

• Entry DOI: 10.2210/pdb3ixa/pdb
• Related: 1DUZ 3H9H
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Tax peptide, ... (5 entities in total)
• Functional Keywords: tel1p, tax, a150p mutation, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 6
• Total formula weight: 90028.12

Authors

Borbulevych, O.Y.,Baker, B.M. (deposition date: 2009-09-03, release date: 2010-01-12, Last modification date: 2023-09-06)

• Primary citation: Borbulevych, O.Y.,Piepenbrink, K.H.,Gloor, B.E.,Scott, D.R.,Sommese, R.F.,Cole, D.K.,Sewell, A.K.,Baker, B.M.; T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.; Immunity, 31:885-896, 2009; PubMed: 20064447; DOI: 10.1016/j.immuni.2009.11.003

Experimental method

X-RAY DIFFRACTION (2.1 Å)