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3ITM

Catalytic domain of hPDE2A

Summary for 3ITM
Entry DOI10.2210/pdb3itm/pdb
Related1Z1L
DescriptorcGMP-dependent 3',5'-cyclic phosphodiesterase, ZINC ION (3 entities in total)
Functional Keywordszn-binding, all-alpha helical, cgmp, hydrolase, membrane
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Peripheral membrane protein (Potential): O00408
Total number of polymer chains4
Total formula weight161162.04
Authors
Pandit, J. (deposition date: 2009-08-28, release date: 2009-10-27, Last modification date: 2024-02-21)
Primary citationPandit, J.,Forman, M.D.,Fennell, K.F.,Dillman, K.S.,Menniti, F.S.
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct.
Proc.Natl.Acad.Sci.USA, 106:18225-18230, 2009
Cited by
PubMed: 19828435
DOI: 10.1073/pnas.0907635106
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.49 Å)
Structure validation

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