3ITM
Catalytic domain of hPDE2A
Summary for 3ITM
Entry DOI | 10.2210/pdb3itm/pdb |
Related | 1Z1L |
Descriptor | cGMP-dependent 3',5'-cyclic phosphodiesterase, ZINC ION (3 entities in total) |
Functional Keywords | zn-binding, all-alpha helical, cgmp, hydrolase, membrane |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Peripheral membrane protein (Potential): O00408 |
Total number of polymer chains | 4 |
Total formula weight | 161162.04 |
Authors | Pandit, J. (deposition date: 2009-08-28, release date: 2009-10-27, Last modification date: 2024-02-21) |
Primary citation | Pandit, J.,Forman, M.D.,Fennell, K.F.,Dillman, K.S.,Menniti, F.S. Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct. Proc.Natl.Acad.Sci.USA, 106:18225-18230, 2009 Cited by PubMed: 19828435DOI: 10.1073/pnas.0907635106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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