1Z1L
The Crystal Structure of the Phosphodiesterase 2A Catalytic Domain
Summary for 1Z1L
Entry DOI | 10.2210/pdb1z1l/pdb |
Descriptor | cGMP-dependent 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pde 2a, phosphodiesterase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Peripheral membrane protein (Potential): O00408 |
Total number of polymer chains | 1 |
Total formula weight | 40490.88 |
Authors | Ding, Y.H.,Kohls, D.,Low, C. (deposition date: 2005-03-04, release date: 2005-06-21, Last modification date: 2023-08-23) |
Primary citation | Iffland, A.,Kohls, D.,Low, S.,Luan, J.,Zhang, Y.,Kothe, M.,Cao, Q.,Kamath, A.V.,Ding, Y.H.,Ellenberger, T. Structural Determinants for Inhibitor Specificity and Selectivity in PDE2A Using the Wheat Germ in Vitro Translation System. Biochemistry, 44:8312-8325, 2005 Cited by PubMed: 15938621DOI: 10.1021/bi047313h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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