1Z1L
The Crystal Structure of the Phosphodiesterase 2A Catalytic Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 345 | 40306.2 | 1 | UniProt (O00408) Pfam (PF00233) | Homo sapiens (human) | Cyclic GMP stimulated phosphodiesterase, CGS-PDE, cGSPDE |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 578 - 919 (UniProt: O00408)
| PDB | External Database | Details |
|---|---|---|
| Met 575 | - | initiating methionine |
| His 576 | - | cloning artifact |
| Ala 577 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40306.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 184.7 | |
| All* | Total formula weight | 40490.9 |
