1Z1L

The Crystal Structure of the Phosphodiesterase 2A Catalytic Domain

Summary for 1Z1L

Entry DOI	10.2210/pdb1z1l/pdb
Descriptor	cGMP-dependent 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	pde 2a, phosphodiesterase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Peripheral membrane protein (Potential): O00408
Total number of polymer chains	1
Total formula weight	40490.88
Authors	Ding, Y.H.,Kohls, D.,Low, C. (deposition date: 2005-03-04, release date: 2005-06-21, Last modification date: 2023-08-23)
Primary citation	Iffland, A.,Kohls, D.,Low, S.,Luan, J.,Zhang, Y.,Kothe, M.,Cao, Q.,Kamath, A.V.,Ding, Y.H.,Ellenberger, T. Structural Determinants for Inhibitor Specificity and Selectivity in PDE2A Using the Wheat Germ in Vitro Translation System. Biochemistry, 44:8312-8325, 2005 Cited by PubMed: 15938621 DOI: 10.1021/bi047313h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation