3HLH

Diisopropyl fluorophosphatase (DFPase), active site mutants

Summary for 3HLH

Entry DOI	10.2210/pdb3hlh/pdb
Related	1E1A 2GVU 2GVV 2GVW 2GVX 3BYC 3HLI
Descriptor	Diisopropyl-fluorophosphatase, CALCIUM ION (3 entities in total)
Functional Keywords	phosphotriesterase, beta propeller, calcium binding, calcium, hydrolase, metal-binding
Biological source	Loligo vulgaris (Common European squid)
Total number of polymer chains	4
Total formula weight	139978.86
Authors	Chen, J.C.-H.,Blum, M.-M. (deposition date: 2009-05-27, release date: 2009-11-10, Last modification date: 2023-11-01)
Primary citation	Melzer, M.,Chen, J.C.,Heidenreich, A.,Gab, J.,Koller, M.,Kehe, K.,Blum, M.M. Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design J.Am.Chem.Soc., 131:17226-17232, 2009 Cited by PubMed: 19894712 DOI: 10.1021/ja905444g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation