3HLH
Diisopropyl fluorophosphatase (DFPase), active site mutants
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Diisopropyl-fluorophosphatase | polymer | 314 | 34914.6 | 4 | UniProt (Q7SIG4) Pfam (PF08450) | Loligo vulgaris (Common European squid) | DFPase |
| 2 | E, F, G, H, I... (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 3 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 907 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 314 (UniProt: Q7SIG4)
| PDB | External Database | Details |
|---|---|---|
| Ala 37 | Glu 37 | engineered mutation |
| Ala 144 | Tyr 144 | engineered mutation |
| Ala 146 | Arg 146 | engineered mutation |
| Met 195 | Thr 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139658.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 320.6 | |
| All* | Total formula weight | 139978.9 |
