3HLI
diisopropyl fluorophosphatase (DFPase), active site mutants
Summary for 3HLI
Entry DOI | 10.2210/pdb3hli/pdb |
Related | 1E1A 2GVU 2GVV 2GVW 2GVX 3BYC 3HLH |
Descriptor | Diisopropyl-fluorophosphatase, CALCIUM ION (3 entities in total) |
Functional Keywords | phosphotriesterase, beta propeller, calcium binding, calcium, hydrolase, metal-binding |
Biological source | Loligo vulgaris (Common European squid) |
Total number of polymer chains | 4 |
Total formula weight | 140154.89 |
Authors | Chen, J.C.-H.,Blum, M.-M. (deposition date: 2009-05-27, release date: 2009-11-10, Last modification date: 2023-11-01) |
Primary citation | Melzer, M.,Chen, J.C.,Heidenreich, A.,Gab, J.,Koller, M.,Kehe, K.,Blum, M.M. Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design J.Am.Chem.Soc., 131:17226-17232, 2009 Cited by PubMed: 19894712DOI: 10.1021/ja905444g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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