3HAE

Rational development of high-affinity T-cell receptor-like antibodies

Replaces:  3GJG

Summary for 3HAE

• Entry DOI: 10.2210/pdb3hae/pdb
• Related: 3GJE 3GJF
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NYESO-1 peptide, ... (5 entities in total)
• Functional Keywords: fab, major histocompatability complex, immunity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 20
• Total formula weight: 362219.02

Authors

Stewart-Jones, G.,Wadle, A.,Hombach, A.,Shenderov, E.,Held, G.,Fischer, E. (deposition date: 2009-05-01, release date: 2009-05-19, Last modification date: 2011-07-13)

• Primary citation: Stewart-Jones, G.,Wadle, A.,Hombach, A.,Shenderov, E.,Held, G.,Fischer, E.,Kleber, S.,Stenner-Liewen, F.,Bauer, S.,McMichael, A.,Knuth, A.,Abken, H.,Hombach, A.A.,Cerundolo, V.,Jones, E.Y.,Renner, C.; Rational development of high-affinity T-cell receptor-like antibodies; Proc.Natl.Acad.Sci.USA, 106:5784-5788, 2009; PubMed: 19307587; DOI: 10.1073/pnas.0901425106

Experimental method

X-RAY DIFFRACTION (2.9 Å)