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3H9S

The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide

Summary for 3H9S
Entry DOI10.2210/pdb3h9s/pdb
Related1AO7 2GJ6 3H7B 3H9H
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Tel1p peptide, ... (7 entities in total)
Functional Keywordstel1p peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains5
Total formula weight94908.04
Authors
Borbulevych, O.Y.,Baker, B.M. (deposition date: 2009-04-30, release date: 2010-01-12, Last modification date: 2023-09-06)
Primary citationBorbulevych, O.Y.,Piepenbrink, K.H.,Gloor, B.E.,Scott, D.R.,Sommese, R.F.,Cole, D.K.,Sewell, A.K.,Baker, B.M.
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31:885-896, 2009
Cited by
PubMed: 20064447
DOI: 10.1016/j.immuni.2009.11.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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