3H00

Structure of the C-terminal Domain of a Putative HIV-1 gp41 Fusion Intermediate

Summary for 3H00

Entry DOI	10.2210/pdb3h00/pdb
Related	3GWO 3H01
Descriptor	Envelope glycoprotein gp160 (2 entities in total)
Functional Keywords	viral membrane fusion, hiv-1, gp41, envelope protein, neutralizing antibodies, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein
Biological source	Human immunodeficiency virus type 1 lw12.3 isolate (HIV-1)
Cellular location	Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626
Total number of polymer chains	4
Total formula weight	19184.62
Authors	Liu, J. (deposition date: 2009-04-08, release date: 2009-12-15, Last modification date: 2023-09-06)
Primary citation	Liu, J.,Deng, Y.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M. Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion. J.Virol., 84:201-209, 2010 Cited by PubMed: 19846514 DOI: 10.1128/JVI.01558-09 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation