3GWO

Structure of the C-terminal Domain of a Putative HIV-1 gp41 Fusion Intermediate

Summary for 3GWO

• Entry DOI: 10.2210/pdb3gwo/pdb
• Related: 3H00 3H01
• Descriptor: Envelope glycoprotein gp160, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), SODIUM ION, ... (4 entities in total)
• Functional Keywords: viral membrane fusion, hiv-1, gp41, envelope protein, neutralizing antibodies, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein
• Biological source: Human immunodeficiency virus type 1 lw12.3 isolate (HIV-1)
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626
• Total number of polymer chains: 2
• Total formula weight: 14909.60

Authors

Liu, J. (deposition date: 2009-04-01, release date: 2009-12-15, Last modification date: 2024-02-21)

• Primary citation: Liu, J.,Deng, Y.,Li, Q.,Dey, A.K.,Moore, J.P.,Lu, M.; Role of a putative gp41 dimerization domain in human immunodeficiency virus type 1 membrane fusion.; J.Virol., 84:201-209, 2010; PubMed: 19846514; DOI: 10.1128/JVI.01558-09

Experimental method

X-RAY DIFFRACTION (1.65 Å)