3GXO
Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A
Summary for 3GXO
Entry DOI | 10.2210/pdb3gxo/pdb |
Related | 3GWZ |
Descriptor | MmcR, S-ADENOSYL-L-HOMOCYSTEINE, [(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate, ... (5 entities in total) |
Functional Keywords | methyltransferase, mitomycin, mmcr, s-adenosyl methionine, transferase |
Biological source | Streptomyces lavendulae |
Total number of polymer chains | 4 |
Total formula weight | 163312.31 |
Authors | Singh, S.,Chang, A.,Bingman, C.A.,Phillips Jr., G.N.,Thorson, J.S. (deposition date: 2009-04-02, release date: 2010-04-21, Last modification date: 2023-11-22) |
Primary citation | Singh, S.,Chang, A.,Goff, R.D.,Bingman, C.A.,Gruschow, S.,Sherman, D.H.,Phillips, G.N.,Thorson, J.S. Structural characterization of the mitomycin 7-O-methyltransferase. Proteins, 79:2181-2188, 2011 Cited by PubMed: 21538548DOI: 10.1002/prot.23040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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