3GXO

Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, C, B	MmcR	polymer	369	40074.3	4	UniProt (Q9X5T6) Pfam (PF00891) In PDB	Streptomyces lavendulae
2	A, D, C, B	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH)
3	A, D, C, B	[(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate	non-polymer		349.3	4	Chemie (MQA)
4	D	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5		water	water		18.0	329	Chemie (HOH)

Sequence modifications

A, D, C, B: 2 - 349 (UniProt: Q9X5T6)

PDB	External Database	Details
Mse -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Mse 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	160297.2
Non-Polymers*	Number of molecules	10
	Total formula weight	3015.2
All*	Total formula weight	163312.3

*Water molecules are not included.