3G6W
Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half
Summary for 3G6W
Entry DOI | 10.2210/pdb3g6w/pdb |
Related | 1VST 1XTT 1XTU 1XTV |
Descriptor | Uracil phosphoribosyltransferase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | allosteric regulation, tetramer, sulfolobus solfataricus, phosphoribosyltransferase, prpp, r5p, gtp, pop, magnesium, glycosyltransferase, transferase |
Biological source | Sulfolobus solfataricus |
Total number of polymer chains | 4 |
Total formula weight | 100729.72 |
Authors | Kadziola, A.,Christoffersen, S. (deposition date: 2009-02-09, release date: 2009-09-01, Last modification date: 2023-11-01) |
Primary citation | Christoffersen, S.,Kadziola, A.,Johansson, E.,Rasmussen, M.,Willemoes, M.,Jensen, K.F. Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus J.Mol.Biol., 393:464-477, 2009 Cited by PubMed: 19683539DOI: 10.1016/j.jmb.2009.08.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report