3G04
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Summary for 3G04
Entry DOI | 10.2210/pdb3g04/pdb |
Related | 1XWD |
Descriptor | HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN, HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN, Thyrotropin receptor, ... (6 entities in total) |
Functional Keywords | tsh receptor, gpcr, thyroid, graves' disease, autoimmunity, receptor-autoantibody complex, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 76128.97 |
Authors | Sanders, J.,Chirgadze, D.Y.,Sanders, P.,Baker, S.,Sullivan, A.,Bhardwaja, A.,Bolton, J.,Reeve, M.,Nakatake, N.,Evans, M.,Richards, T.,Powell, M.,Miguel, R.N.,Blundell, T.L.,Furmaniak, J.,Smith, B.R. (deposition date: 2009-01-27, release date: 2009-08-04, Last modification date: 2023-11-01) |
Primary citation | Sanders, J.,Chirgadze, D.Y.,Sanders, P.,Baker, S.,Sullivan, A.,Bhardwaja, A.,Bolton, J.,Reeve, M.,Nakatake, N.,Evans, M.,Richards, T.,Powell, M.,Miguel, R.N.,Blundell, T.L.,Furmaniak, J.,Smith, B.R. Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody Thyroid, 17:395-410, 2007 Cited by PubMed: 17542669DOI: 10.1089/thy.2007.0034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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